Rick Santorum has a very good chance of scoring a major victory in Saturday’s Republican presidential primary in Louisiana, but the big question is whether it will still matter.

Polls released the past couple of days indicate the former senator from Pennsylvania with a double-digit lead over former Massachusetts Gov. Mitt Romney and former House Speaker Newt Gingrich, among those likely to vote in Louisiana’s contest.

But since Romney’s 12-point victory over Santorum, his nearest rival in the battle for the GOP nomination, in the Illinois primary on Tuesday, the conversation appears to have changed.

“Santorum can’t lose this and it doesn’t look like he will. He will argue that the victory proves Romney can’t win in the South, the bedrock of the Republican Party. But will anyone be listening,” CNN Chief Political Correspondent Candy Crowley said. “Inside the party, there is a full-blown push to close this thing down,” evidenced by the support for Romney from Jeb Bush and Jim DeMint.

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